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CV and mad panic behaviour
Firstly no Vaccines wane, vaccine effectiveness remains against the targeted strain but viral strains evolve.

Resistance from vaccination may diminish, but the immune system is complex and the measures of resistance only survey small parts of the immune system like neutralizing antibodies.

In Silico(computer) and In Vitro(Petri dish) and not the same as In Situ/Vivo(people).

Vaccines like Influenza are often a blend of new and old vaccines design to target In Silico predictions of viral evolution.

Resistance from immunization is a variable person to person, the best evidence comes from the billions of immunized people not dying or being hospitalized.

Infections are only part of the story because viral load matters, vaccination remains efficacious at reducing acute symptoms and viral load months or years after immunization.

Neutralizing antibody counts can fully or fractionally diminish over time, but that is only the simplest available measure, B-cell and T-cell immunity remains and it is the combination of many factors that deliver efficacy. Efficacy is not just a measure of antibody levels but a complex array of effectiveness measures.
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Drugs shown to have some efficacy In Silico or In Vitro do not always work In Situ/Vivo, in fact most do not!

Example Ivermectin is a demonstrated 3CL Protease inhibitor In Silico, and at ridiculously high dose In Vitro it kills a virus like Sars-CoV-2, but at safe dose In Situ/Vivo it did nothing, it was worse than chance. And they have tested it in millions of people now either through the actions of nefarious despots or very large trials.

Now that doesn't mean they won't find a way to combine and deliver Ivermectin in some way to specifically target Sars-CoV-2, but for now that mechanism doesn't exist. But we should hope they do find a way because it might be cheaper solution!

Proving 3CL Protease inhibition does not prove efficacy, it is just a broad label. Like pieces of metal shaped into keys that superficially look the same they can be cut subtly differently and as such one key does not work opening every lock. If being labelled a 3CL Protease Inhibitor was all you need there are dozens of drugs that should work, but no one drug works on every virus, it is not as simple as applying the broad label suggests.
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And for the shills - Ivermectin vs Pfizermectin.

Follow the $$$$.

https://www.youtube.com/watch?v=ufy2AweXRkc
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(11-12-2021, 12:11 PM)DJC link Wrote:Well, none of the COVID vaccines are dead useless after 6 months but the flu vaccine is. 

The facts don't support your position Flyboy and conspiracy theories don't cut the mustard.  Unless you can come up with empirical evidence it's probably best just to fade away.

Is that right David. If you don't read what I put up you really are not well placed to comment.

Excess deaths and excess numbers of weird illnesses are just conspiracy?

You clearly have trouble interpreting government sourced data?

Let me know which chart or table you need help understanding?
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(11-12-2021, 05:47 PM)LP link Wrote:Drugs shown to have some efficacy In Silico or In Vitro do not always work In Situ, in fact most do not!

Example Ivermectin is a demonstrated 3CL Protease inhibitor In Silico, and at ridiculously high dose In Vitro it kills a virus like Sars-CoV-2, but at safe dose In Situ it did nothing, it was worse than chance. And they have tested it in millions of people now either through the actions of nefarious despots or very large trials.

Now that doesn't mean they won't find a way to combine and deliver Ivermectin in some way to specifically target Sars-CoV-2, but for now that mechanism doesn't exist. But we should hope they do find a way because it might be cheaper solution!

Proving 3CL Protease inhibition does not prove efficacy, it is just a broad label. Like pieces of metal shaped into keys that superficially look the same they can be cut subtly differently and as such one key does not work opening every lock. If being labelled a 3CL Protease Inhibitor was all you need there are dozens of drugs that should work, but no one drug works on every virus, it is not as simple as applying the broad label suggests.

The high dose claim is just another lie.

Ivermectin has been used widely and very successfully to treat CV19. Why deny it?

c19ivermectin.com

https://covid19criticalcare.com/covid-19-protocols/
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David says:

Quote:Well, none of the COVID vaccines are dead useless after 6 months but the flu vaccine is.

Your government says:

"Get a CV19 booster no later than 6 months after your last jab otherwise you're regarded as unvaxxed."

I wonder why that would be?

LP must know surely.

Maryanne Demasi says - https://maryannedemasi.com/publications/...y=COVID-19
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Worth watching the first 15 minutes or so (if you're in a hurry).

This is the guy developing the COVAX vaccine in Adelaide.

https://www.youtube.com/watch?v=9x2ieHuj8zU

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(11-12-2021, 10:14 PM)flyboy77 date Wrote:The high dose claim is just another lie.

Ivermectin has been used widely and very successfully to treat CV19. Why deny it?

c19ivermectin.com

https://covid19criticalcare.com/covid-19-protocols/
Bad news, Brazil and India say hello, even at normal or in India's case about 15x normal dose levels! ;D

Quote:It was a mix of vitamins and other pills that President Jair Bolsonaro touted as early treatments for COVID-19, well before vaccines became widely available to prevent and minimize coronavirus infections.

Among the “kit” drugs were the malaria pill hydroxychloroquine and the antiparasitic tablet ivermectin.

Brazilian authorities even at one point launched an app, called TrateCov, (“TreatCov[id]” in English) which recommended the same seven “kit” drugs to all its users. (The evidence base for that protocol leaned heavily on data from Dr. Flávio Cadegiani, who’s now a member of the FLCCC, a US-based ivermectin propaganda machine.)

But Brazilians quickly discovered – through heart-wrenching personal experience – the limits of treating COVID-19 with ivermectin. Brazil suffered some of its worst death rates yet in late 2020 and early 2021, even in heavily ivermectin-dosed areas, as the more transmissible P1 variant spread quickly across the country.

The biggest Ivermectin experiments on earth missed it by that much, massive fail for reasons I've already addressed above, not all protease inhibitors are equal, case closed!

Since he started his Ivermectin / Pfizer rant Dr John Campbell has been questioned about Brazil and India multiple times, yet he refuses to address the Ivermectin it in his videos and continues on with his anti-Pfizer rant! Unfortunately it probably exposes him as a paranoid big pharma conspiracist which will no doubt devalue some of his earlier good work. I suppose everyone can fall off the rails after a bout of illness! Wink
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Maryanne Demassi is your poster girl for truth…?
How’s your wifi signal ?
???

Let’s go BIG !
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I dont know much, but what I've seen is over the last 2 years, painters, electricians and mechanics seem to have more health advice regarding a pandemic with categorical statements of fact than any medical professionals i know which is cause enough to state with accuracy that there is no miracle drug out there that works irrespective of the assertions.
"everything you know is wrong"

Paul Hewson
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