CV and mad panic behaviour

[LP]

There is a bit of a social media movement pushing 3CL protease inhibitors, actually any protease inhibitor but mostly Ivermectin, it is a gross oversimplification of reality.

Yes, many drugs are protease inhibitors, and inhibiting protease can stop viral replication. But not every drug that can inhibit protease works to stop every virus. The spurious claims are misleading, like Dr John Campbell's reference to molecule and carbon atom counts. So I'll make a simple analogy as a counterpoint.

Two houses can have the same number and shape ceramic tiles in the same mix of colours, but one may be a T shaped hip roof from 1980, and the other a cathedral gable from 1876! Counting tiles is not a valid description of the structure.

We know many protease inhibitors do squat, even others do plenty but will kill you faster than the virus, it all comes down to that structure! That is why the devil is in the detail. For a protease inhibitor to work it has to have both the correct structure to get where it needs to be, and be inserted at exactly the right moment, otherwise the virus will most likely replace it as that is what a virus does.